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COMISION NACIONAL DE ENERGIA ATOMICA
Conocimiento de la energía nuclear para fines pacíficos
 
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 CNEA --> BNCT --> Publicaciones  

Publicaciones

• M.A. Pisarev, M.A. Dagrosa, G.J.Juvenal. “Boron Neutron Capture Therapy in Cancer: Past, Present and Future”. Arq. Bras. Endocrinol. Metad.; 51/5: 852-856 (2007).

• E.M. Heber, R.F. Aromando, V.A. Trivillin, M.E. Itoiz, D.W. Nigg, E.L. Kreiman, A.E. Schwint. “Therapeutic effect of boron neutron capture therapy (BNCT) on field cancerized tissue: inhibition of DNA synthesis and lag in the development of second primary tumors in precancerous tissue around treated tumors in DMBA-induced carcinogenesis in the hamster cheek pouch oral cancer model”. Archives Oral Biology 52:273-279 (2007).

• J.E. Cardoso, V.A. Trivillin, E.M. Heber, D.W. Nigg, O. Calzetta, H. Blaumann, J. Longhino, M.E. Itoiz, E. Bumaschny, E. Pozzi, A.E. Schwint. “Effect of Boron Neutron Capture Therapy (BNCT) on Normal Liver Regeneration: Towards a Novel Therapy for Liver Metastases”.
International Journal of Radiation Biology 83:10, 699-706 (2007).

• E.A. Gautier, M.J. Roberti, R.T. Gettar, R. Jiménez Rebagliati, D.A. Batistoni. “Assessment of chemical purity of 10B-enriched p-boronophenylalanine by high-performance liquid chromatography coupled on-line with inductively coupled plasma optical emission spectrometry”. Anal. Bioanal. Chem. 388:499-503 (2007).

• V.A. Trivillin, E.M. Heber, M. Rao, M.A. Cantarelli, M.E. Itoiz, D.W. Nigg, O. Calzetta, H. Blaumann, J. Longhino, A.E. Schwint. “Boron Neutron Capture Therapy (BNCT) for the treatment of spontaneous nasal planum Squamous Cell Carcinoma in felines”. Radiation and Environmental Biol. Physics 2007 (en prensa).

• M. Pisarev, G. Juvenal, A. Dagrosa., L. Thomasz., J. Longhino, M. Perona, O. Calzetta, H. Blaumann, R. Jiménez Rebagliati, R. Cabrini, S. Khal. “Optimization of the Application of Boron Neutron Capture Therapy (BNCT) to the Treatment of Undifferentiated Thyroid Cancer (UTC)”. Int. J. of Radiat. Oncol. Biol. Phys. 2007 (en prensa).

• E.M. Heber, V.A. Trivillin, D.W. Nigg, M.E. Itoiz, B.N. González, R.J. Rebagliati, D. Batistoni, E.L. Kreimann, A.E. Schwint. “Homogeneous boron targeting of heterogeneous tumors for Boron Neutron Capture Therapy (BNCT): chemical analyses in the hamster cheek pouch oral cancer model”. Archives of Oral Biology 51: 922-929 (2006).

• V.A. Trivillin, E.M. Heber, D.W. Nigg, M.E. Itoiz, O. Calzetta, H. Blaumann, J. Longhino, A.E. Schwint. “Therapeutic success of Boron Neutron Capture Therapy (BNCT) mediated by a chemically non-selective boron agent in an experimental model of oral cancer: A new paradigm in BNCT radiobiology”. Radiation Research 166: 387-396 (2006).

• M. Agote Robertson, P. Finochietto, C.A. Gamba, M.A. Dagrosa, M. Viaggi, M.C. Franco, J.J. Poderoso, G.J. Juvenal, M.A. Pisarev. “Nicotinamide increases thyroid radiosensitivity by stimulating nitric oxide Synthase expression and the generation of organic peroxides”. Horm. & Metab. Res 38:12, 2006.

• M.A. Pisarev, M.A. Dagrosa, G.J. Juvenal. “Application of borono neutron capture therapy tothe treatment of anaplastic Thyroid carcinoma: current status and future perspectives”. Current Op. In Endocrinol. 12: 352, 2006.

• A.A. Burlon, A.J. Kreiner, A.A. Valda, D.M. Minsky, H.R. Somacal, M.E. Debray, P. Stoliar. “Optimization of a Neutron Production Target and Beam Shaping Assembly Based on the 7Li(p,n)7Be Reaction”. Nuclear Instruments and Methods in Physics Research B, 229, 144-156 (2005)

• A. Valda, D.M. Minsky, A.J. Kreiner, A.A. Burlon, H. Somacal. “Development of a Tomographic System for Online Dose Measurements in BNCT (Boron Neutron Capture Therapy)”. Brazilian Journal of Physics, 35, 3B, 785-788 (2005)

• M.A. Dagrosa, M. Viaggi, R. Jiménez Rebagliati, D. Batistoni, S.B. Kahl, G.J. Juvenal, M.A. Pisarev. “Biodistribution of Boron Compounds in an Animal Model of Undifferentiated Thyroid Cancer for Boron Neutron Capture Therapy”. Molecular Pharmaceutic, 2, 151-156 (2005)

• M.A. Pisarev, M.A. Dagrosa, G.J. Juvenal. “Application of Boron Neutron Capture Therapy to the Treatment of Anaplastic Thyroid Carcinoma: Current Status and Future Perspectives”. Current Opinion in Endocrinology and Diabetes, 12, 352-355 (2005)

• S.J. González, D.G. Carando, G.A. Santa Cruz, R.G. Zamenhof. “Voxel Model in BNCT Treatment Planning: Performance Analysis and Improvements”. Physics in Medicine and Biology, 50, 441-458 (2005).

• E. Heber, V. A. Trivillin, D. Nigg, E. L. Kreimann, M. E. Itoiz, R. J. Rebagliati, D. Batistoni, A. E. Schwint. “Biodistribution of GB-10 (Na2 10B10H10) Compound for Boron Neutron Capture Therapy (BNCT) in an Experimental Model of Oral Cancer in the Hamster Cheek Pouch”. Archives of Oral Biology, 49, 313-324 (2004)

• P. Stoliar, A. J. Kreiner, M. E. Debray, M. E. Caraballo, A. A. Valda, J. Davidson, M. Davidson, J. M. Kesque, H. Somacal, H. DiPaolo, A. A. Burlon, M. J. Ozafrán, M. E. Vázquez, D. Minsky , E. M. Heber, V. A. Trivillin, A. E. Schwint. “Microdistribution of Prospective BNCT-compound CuTCPH in Tissue Sections with a Heavy Ion Microbeam”. Applied Radiation and Isotopes. 61, 771-774 (2004).

• M. R. Casal, S. J. González, H. R. Blaumann, J. Longhino, O. A. Calzetta Larrieu, C. A. Wemple. “Comparison of the Performance of Two NCT Treatment Planning Systems Using the Therapeutic Beam of the RA-6 Reactor”. Applied Radiation and Isotopes. 61, 805-810 (2004).

• A. A. Burlon, A. J. Kreiner, A. A. Valda, D. M. Minsky. “An Optimized Neutron-beam Shaping Assembly for Accelerator-based BNCT”. Applied Radiation and Isotopes. 61, 811-815 (2004).

• H. R. Blaumann, D. E. Sanz, J. M. Longhino, O. A. Calzetta Larrieu. “BNCT Dose Calculation in Irregular Fields Using the Sector Integration Method”. Applied Radiation and Isotopes. 61, 835-840 (2004).

• M. Viaggi, M. A. Dagrosa, J. Longhino, H. Blaumann, O. Calzetta, S. B. Kahl, G. J. Juvenal, M. A. Pisarev. “Boron Neutron Capture Therapy For Undifferentiated Thyroid Carcinoma: Preliminary Results with the Combined Use of BPA and BOPP”. Applied Radiation and Isotopes. 61, 905-909 (2004)

• M. A. Dagrosa, M. Viaggi, R. Jimenez Rebagliati, V. A. Castillo, D. Batistoni, R. L. Cabrini, S. Castiglia, G. J. Juvenal, M. A. Pisarev. “Biodistribution of p-borophenylalanine (BPA) in Dogs with Spontaneous Undifferentiated Thyroid Carcinoma (UTC)”. Applied Radiation and Isotopes. 61, 911-915 (2004).

• S. J. González, D. G. Carando, M. R. Bonomi. “A New Approach to Determine Tumor-to-blood 10B Concentration Ratios from the Clinical Outcome of a BNCT Treatment” Applied Radiation and Isotopes. 61, 923-928 (2004).

• V. A. Trivillin, E. M. Heber, M. E. Itoiz, D. Nigg, O. Calzetta, H. Blaumann, J. Longhino, A E. Schwint. “Radiobiology of BNCT Mediated by GB-10 and GB-10 + BPA in Experimental Oral Cancer”. Applied Radiation and Isotopes. 61, 939-945 (2004).

• M. Rao, V. A. Trivillin, E. M. Heber, M. A. Cantarelli, M. E. Itoiz, D. W. Nigg, R. Jiménez Rebagliati, D. Batistoni, A. E. Schwint. “BNCT of 3 Cases of Spontaneous Head and Neck Cancer in Feline Patients”. Applied Radiation and Isotopes. 61, 947-952 (2004).

• M. E. Miller, L. E. Mariani, M. L. Sztejnberg Gonçalves-Carralves, M. Skumanic, S. I. Thorp. “Implantable Self-powered Detector for On-line Determination Of Neutron Flux in Patients During NCT Treatment”. Applied Radiation and Isotopes. 61, 1033-1037 (2004).

• S. J. Liberman, A. Dagrosa, R. A. Jiménez Rebagliati, M. R. Bonomi, B. M. Roth, L. Turjanski, S. J. Castiglia, S. González, P. R. Menéndez, R. Cabrini , M. J. Roberti, D. A. Batistoni. “Biodistribution Studies of Boronophenylalanine-fructose in Melanoma and Brain Tumor Patients in Argentina.” Applied Radiation and Isotopes. 61, 1095-1100 (2004).

• S. J. González, M. R. Bonomi, G. A. Santa Cruz, H. R. Blaumann, O. A. Calzetta Larrieu, P. Menéndez, R. Jiménez Rebagliati, J. Longhino, D. B. Feld, M. A. Dagrosa, C. Argerich, S. G. Castiglia, D. A. Batistoni, S. J. Liberman, B. M. C. Roth. “First BNCT Treatment of a Skin Melanoma in Argentina: Dosimetric Analysis and Clinical Outcome”. Applied Radiation and Isotopes. 61, 1101-1105 (2004).

• H. R. Blaumann, S.J. González, J. Longhino, G. A. Santa Cruz, O. A. Calzetta Larrieu, M. R. Bonomi, B. M. C. Roth. “Boron Neutron Capture Therapy of Skin Melanomas at the RA-6 Reactor: A Procedural Approach to Beam Set Up and Performance Evaluation for Upcoming Clinical Trials”. Medical Physics. 31, 70-80 (2004)

• M. Di Giorgio, A. A. Edwards, J. E. Moquet, P. Finnon, P. A. Hone, D. C. Lloyd, A. J. Kreiner, J. A. Schuff, M. R. Taja, M. B. Vallerga, F. O. López, A. Burlon, M. E. Debray, A. Valda. “Chromosome Aberrations Induced in Human Lymphocytes by Heavy Charged Particles in Track Segment Mode”. Radiation Protection Dosimetry. 108, 47-53 (2004)

• G. A. Santa Cruz, R. G. Zamenhof. "The Microdosimetry of the 10B Reaction in Boron Neutron Capture Therapy: A New Generalized Theory". Radiation Research. 162, 702-710 (2004)

• E. Kreinmann, M. Miura, M. Itoiz, E. Heber, R. Garavaglia, D. Batistoni, R. Jimenez Rebagliatti, M. Roberti, P. Micca, J. Coderre, A. Schwint. Biodistribution of a Carborane Containing Porphirin as a Targeting Agent for Boron Neutron Capture Therapy of Oral Cancer in the Hamster Cheek Pouch. Archives Of Oral Biology 48, 223-323 (2003).

• M. Viaggi, A. Dagrosa, C. Belli, I. Larripa, D. Gangitano, R. Cabrini, M. Pisarev, G. Juvenal New Animal Model for Human Undifferentiated Thyroid Carcinoma. Thyroid 13:529, 2003.

• A. Dagrosa, M. Viaggi, J. Longhino, O. Calzetta, M. Edriera, R. Cabrini, G. Juvenal, M. Pisarev. Experimental Application of BNCT to Undifferentiated Thyroid Carcinoma (UTC). Internat. J. Radiat-.Oncol. Biol. Physics 57:1084, 2003.

• S. Liberman. Terapia para el Cáncer por Captura Neutrónica: Desarrollo en la Comisión Nacional de Energía Atómica. Revista de la CNEA Año III, Número 9/10; 17-21 (Enero-Junio/2003).

• A. Dagrosa, M. Viaggi, R. Cabrini, J. Dadino, G. Juvenal, M. Pisarev. Selective Uptake of p-Borophenylalanine (BPA) by Undiferentiated Carcinoma for Boron Neutron Capture Therapy. Thyroid 12(1): 7-12 (2002).

• G. Santa Cruz, M. Palmer, E. Matatagui, R. Zamenhof. A Theoretical Model for the Microdosimetry of Discontinuous Distributions of Heavy Particle Tracks. Radiation Protection Dosimetry, 99(1-4), 429-431 (2002).

• R. Garavaglia, R. Jiménez Rebagliati, M Roberti, D. Batistoni. Matrix effects in the analysis of biological matrices by axial view inductively coupled plasma-optical emission spectrometry. Spectrochimica Acta B, 57(12) 1925-1938 (2002).

• E. Kreinmann, M. Miura, M. Itoiz, E. Heber, R. Garavaglia, D. Batistoni, R. Jimenez Rebagliatti, M. Roberti, P. Micca, J. Coderre, A. Schwint. Biodistribution of a Carborane Containing Porphirin as a Targeting Agent for Boron Neutron Capture Therapy of Oral Cancer in the Hamster Cheek Pouch. Archives Of Oral Biology 48, 223-323 (2003).

• J. Schuff, L. Policastro, H. Durán, A. Kreiner, A. Mazal, B. Molinari, A. Burlón, M. Debray, J. Kesque, H. Somacal, P. Stoliar, A. Valda, O. Bernaola, A. Perez de la Hoz, G. Saint-Martin, S. O’Connor, J. Davidson, M. Davidson, F. Naab, M. Ozafrán, M. Vázquez, S. Cáneva, S. Delacroix, F. Favaudon, Y. Henry, C. Nauraye, E. Brune, C. Gautier, J. Habrand, M. Palmieri, M. Ruffolo. Relative biological effectiveness measurements of low energy proton and lithium beams on tumor cells, Nucl. Instr. and Meth. in Phys. Res.B Vol. 187(3) (2002) pp. 345-353

• A.J.Kreiner, A.A. Burlón, Novel applications of particle accelerators to radiotherapy. Heavy Ion Physics 16/1-4, 243-256 (2002).

Research and Developement in Neutron Capture Therapy. Editors W. Sauerwein, R. Moss and A. Wittig. Monduzzi Editore, Italia 2002

• W. Kiger, G. Santa Cruz, S. González, F.-Y.Hsu, K. Riley, P. Binns, O. Harling, M. Palmer, P. Busse, R. Zamenhof. Verification and Validation of the NCTPlan Treatment Planning Program. (p.613-616).

• S. González, G. Santa Cruz, W. S. Kiger, R. Zamenhoff. A New Computational Tool for Constructing Dose - Volume Histograms Using Combinatorial Techniques. (p.629-633).

• G. Santa Cruz, R. Zamenhof. A Theoretical Formalism to Extrapolate Measured CBE Factors to Different Conditions of Geometry and 10B Distribution. (p.691-696).

• S. González, G.A. Santa Cruz, W. Kiger, J.T. Goorley, M. Palmer, P.M. Busse, R. Zamenhof. NCTPlan, The New PC Version Of MacNCTPlan: Improvements and Verification of a BNCT Treatment Planning System. (p.557-561).

• E. Heber, E. Kreimann, D. Nigg, M. Itoiz, R. Garavaglia, M. Roberti, R. Jiménez Rebagliati, R. Gettar, D. Batistoni, A. Schwint. Biodistribution Study of GB-10 Compound (Na2 10B10H10) in an Experimental Model of Oral Cancer in the Hamster Cheek Pouch. (p.745-749).

• A. Dagrosa, M. Viaggi, J. Longhino, O. Calzetta, M. Edriera, R. Cabrini, G. Juvenal, M. Pisarev. Experimental application of BNCT to undifferentiated thyroid carcinoma (UTC). (p.685-690).

• P. Busse, O. Harling, M. Palmer, W. Kiger, J. Kaplan, I. Kaplan, C. Chuang,, J. Goorley, K. Riley, T. Newton, G. Santa Cruz, X.Q. Lu, R. Zamenhof. A critical examination of the results from the Harvard MIT NCT Program Phase I Clinical Trial of NCT for Intracraneal Disease (p.1123-1127).

• E. Matatagui, M. Miller, S. Thorp, C. Venastro, J. Villanueva. Special Instrumentation for NCT. (p. 341-345).

• O. Calzetta Larrieu, H. Blaumann, J. Longhino. RA-6 Reactor Mixed Beam Design and Performance for NCT Trials. (p. 155-158).

• A. Burlón, A. Kreiner, A. Valda, D. Minsky, H. Somacal, M. Debray, J. Kesque, P. Stoliar, J. Davidson, M. Davidson, M. Ozafrán, J. Schuff, M. Vázquez. Optimization of a neutron production target and beam shaping assembly based on the 7Li(p,n)7Be reaction. (p. 229-234).

• J. Schuff, L. Policastro, H. Durán, A. Kreiner, A. Mazal, B. Molinari, A. Burlón, J. Davidson, M. Davidson, M. Debray, M. Edreira, J. Kesque, M. Ozafrán, E. Rivera, H. Somacal, P. Stoliar, A. Valda, M. Vázquez. RBE measurements of low energy proton and lithium beams on melanoma cell lines. (p. 701-707).

• F-Y. Hsu, M.Palmer, W. Kiger, G. Santa Cruz, S. González, P. Busse, R. Zamenhof. Comparison of Two BNCT Treatment Planning Codes: NCTPlan and MacNCTPlan. (p.563-567).

• O. Harling, K. Riley, P. Binns, W. Kiger, J. Capala, V. Giusti, P. Munck af Rosenschold, K. Skold, I. Auterinen, T. Seren, P. Kotiluoto, J. Uusi-Simola, T. Seppala, M. Marek, l. Viererbl, F. Spurny, F. Stecher-Rasmussen, W. Voorbraak, J. Morrissey, R. Moss, O. Calzetta Larrieu, H. Blaumann, J. Longhino. International Dosimetry Exchange: A Status Report. (p.333-339).

• J. Longhino, O. Calzetta Larrieu, H. Blaumann. Experimental Determination of the Termal Neutron Sensivity of a TE Ionization Chamber (p.489-493).

• M.A. Dagrosa, M. Viaggi, E. Kreimann, S. Farías, R. Garavaglia, M. Agote, R.L. Cabrini, J.L. Dadino, J.L. Juvenal, M.A. Pisarev. Selective Uptake of p-Borophenylalanine (BPA) by Undifferentiated Carcinoma for Boron Neutron Capture Therapy. Thyroid 12(1): 7-12 (2002)

• E. Kreimann, M. Itoiz, A. Dagrosa, R. Garavaglia, S. Farias, D. Batistoni, A. Schwint. The Hamster Cheek Pouch as a Model of Oral Cancer for Boron Neutron Capture Therapy Studies: Selecive Delivery of Boron by Boronophenylalanine. Cancer Research 61: 8775-8781.(2001)

• E. Kreimann, M. Itoiz, J. Longhino, H. H.Blaumann, O. Calzetta, A.Schwint. Boron Neutron Capture Therapy for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model. Cancer Research 61: 8638-8642.(2001)

• S. Garbe, J. Rassow, C. Vroegindeweij, R. Moss, K. Hideghéty, W. Sauerwein, C. Kessler, F. Stecher-Rasmussen. Radioprotection Dosimetry in the European trial on BNCT Studied by an Anthropomorphic Phantom. Frontiers in Neutron Capture Therapy, edited by Hawthorne et al. Kluwer Academic / Plenum Publishers, New York, Volumen 1: 665-670.(2001)

• H. Blaumann, O. Calzetta Larrieu, J. Longhino, A. Albornoz. NCT Facility Developement and Beam Characterisation at the RA-6 Reactor.Frontiers in Neutron Capture Therapy, edited by Hawthorne et al. New York, Volumen 1: 313-317 (2001)

• J.A. Schuff, L.Policastro, H. Durán, A.J. Kreiner, A. Mazal, B.L. Molinari, A. Burlón, M.E. Debray, J.M.Kesque, H. Somacal, P.Stoliar, A. Valda, O.A. Bernaola, A. Perez de la Hoz, G. Saint-Martin, S.O'Connor, J. Davidson, F. Naab, M.J. Ozafran, M.E. Vazquez, S. Cáneva, S. Delacroix, F. Favaudon, Y. Henry, C.Nauraye, E.Brune, C. Gautier, J.H. Habrand, M. Palmieri, M. Ruffolo Relative Biological Effectiveness Measurements of Low Energy Proton and Lithium Beams on Tumor Cells. (En Prensa) Nuclear Instruments and Methods (2001).

• A.A. Burlón, A.J. Kreiner, S. White, B. Blackburn, D. Gierga, J.C. Yanch. In Phantom Dosimetry Using the 13C(d,n)14N Reaction as Source for Acelerator-based BNCT. Medical Pshysics 28(5): 796-803 (2001)

• G. Santa Cruz, Mattthew Palmer, E. Matatagui, Robert Zamenhof. A Theoretical Model for Event Statistic in Microdosimetry, Part I-Uniform Distribution of Heavy Ion Tracks.Medical Pshysics 28(6): 988-996 (2001)

• G. Santa Cruz, Mattthew Palmer, E. Matatagui, Robert Zamenhof. A Theoretical Model for Event Statistic in Microdosimetry, Part II: Non-Uniform Distribution of Heavy Ion Tracks. Medical Physics 28(6): 997-1005 (2001)

• J. A. Sintas, N. J. Macareno, A. A. Vitale. Synthesis of 8-[10B] - Dihdroxyboryl-Harmine, a Potential Agent For Boron Neutron Capture Therapy. J. Labelled Compounds. Radiopharm. 43: 97-101 (2000).

• M.A. Dagrosa, M. Viaggi, E. Kreimann, S. Farías, R. Garavaglia, M. Agote, R.L. Cabrini, J.L. Dadino, J.L. Juvenal, M.A. Pisarev. Perspectives of a New Treatment Modality For Undifferentiated Thyroid Cancer. Endocrine Journal, vol.47, suppl. (2000)

• R.F. Barth, A.H. Soloway, M.A. Pisarev. Terapia por captura de neutrones en boro (BNCT) en tumores de cerebro: estado actual y potencial futuro. Oncología, 21(11: 1-13) (1998).

• D. Bustos, O. Calzetta Larrieu, H. Blaumann. Epithermal Beam at RA-6 Reactor. B. Larsson, J. Crawford and R. Weinreich (eds) Advances in Neutron Capture Therapy. Amsterdam, Elsevier Science. Volumen 1: 420-423 (1997). (Conference Proceedings)


 

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 Proyecto BNCT en la CNEA
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